ABSTRACT
Objective: The relationship between Socio-Economic Status (SES) and the factors that may play a role in orthodontic treatment demand and uptake have not been explored. Such information is needed for better planning of orthodontic services and to ensure that health care is provided equally among all social classes. The objective of this systematic review was to find out whether socioeconomic status affects the treatment needs of orthodontic patients. Methods: Literature search was done using Medical Subject Heading terms (MeSH) in PubMed, LIVIVO, Google Scholar, and EbscoHost from 1 January 1965 to 1 August 2021. All cross-sectional studies were included. Both male and female participants were included in the review. The quality of assessment for the included studies was evaluated independently by two reviewers using "The Jonna Briggs Institute" tool (JBI) for cross-section studies. The Cochrane Collaboration's tool was modified and used for assessing the risk of bias and risk of summary. Results: A total of 704 articles were found. The relevant database searches were PubMed 259 articles, followed by EbscoHost 280, LIVIVO 145, and Google Scholar 20 articles. A final of 10 cross-sectional studies were included in the review. Conclusion: The reviewers found evidence that parents ultimately decide whether the child will undergo treatment, possibly depending on their financial situation.
ABSTRACT
This study undertook a review of the literature on drug treatment of oral submucous fibrosis. An electronic search was carried out for articles published between January 1960 to November 2011. Studies with high level of evidence were included. The levels of evidence of the articles were classified after the guidelines of the Oxford Centre for Evidence-Based Medicine. The main outcome measures used were improvement in oral ulceration, burning sensation, blanching and trismus. Only 13 publications showed a high level of evidence (3 randomized controlled trials and 10 clinical trials/controlled clinical trials), with a total of 1157 patients. Drugs like steroids, hyaluronidase, human placenta extracts, chymotrypsin and collagenase, pentoxifylline, nylidrin hydrochloride, iron and multivitamin supplements including lycopene, have been used. Only systemic agents were associated with few adverse effects like gastritis, gastric irritation and peripheral flushing with pentoxifylline, and flushingly warm skin with nylidrin hydrochloride; all other side-effects were mild and mainly local. Few studies with high levels of evidence were found. The drug treatment that is currently available for oral submucous fibrosis is clearly inadequate. There is a need for high-quality randomized controlled trials with carefully selected and standardized outcome measures.
